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HiFi sequencing for AAV gene therapy: from discovery and design to  production - PacBio
HiFi sequencing for AAV gene therapy: from discovery and design to production - PacBio

AAV genome organization and integration capture sequencing schematic.... |  Download Scientific Diagram
AAV genome organization and integration capture sequencing schematic.... | Download Scientific Diagram

ITR-Seq, a next-generation sequencing assay, identifies genome-wide DNA  editing sites in vivo following adeno-associated viral vector-mediated  genome editing | BMC Genomics | Full Text
ITR-Seq, a next-generation sequencing assay, identifies genome-wide DNA editing sites in vivo following adeno-associated viral vector-mediated genome editing | BMC Genomics | Full Text

scAAVengr, a transcriptome-based pipeline for quantitative ranking of  engineered AAVs with single-cell resolution | eLife
scAAVengr, a transcriptome-based pipeline for quantitative ranking of engineered AAVs with single-cell resolution | eLife

AAV-Genome Population Sequencing of Vectors Packaging CRISPR Components  Reveals Heterogeneity - YouTube
AAV-Genome Population Sequencing of Vectors Packaging CRISPR Components Reveals Heterogeneity - YouTube

Adeno-associated Virus Genome Population Sequencing Achieves Full Vector  Genome Resolution and Reveals Human-Vector Chimeras: Molecular Therapy -  Methods & Clinical Development
Adeno-associated Virus Genome Population Sequencing Achieves Full Vector Genome Resolution and Reveals Human-Vector Chimeras: Molecular Therapy - Methods & Clinical Development

Viral Genome Sequencing - A One Stop Shop for AAV Identity and Serotype  Confirmation
Viral Genome Sequencing - A One Stop Shop for AAV Identity and Serotype Confirmation

Viruses | Free Full-Text | Satellite Subgenomic Particles Are Key  Regulators of Adeno-Associated Virus Life Cycle
Viruses | Free Full-Text | Satellite Subgenomic Particles Are Key Regulators of Adeno-Associated Virus Life Cycle

Drawing a high-resolution functional map of adeno-associated virus capsid  by massively parallel sequencing | Nature Communications
Drawing a high-resolution functional map of adeno-associated virus capsid by massively parallel sequencing | Nature Communications

GENEWIZ from Azenta | AAV Plasmid Synthesis
GENEWIZ from Azenta | AAV Plasmid Synthesis

JCI Insight - Using a barcoded AAV capsid library to select for clinically  relevant gene therapy vectors
JCI Insight - Using a barcoded AAV capsid library to select for clinically relevant gene therapy vectors

A Novel Next-Generation Sequencing and Analysis Platform to Assess the  Identity of Recombinant Adeno-Associated Viral Preparations from Viral DNA  Extracts | Human Gene Therapy
A Novel Next-Generation Sequencing and Analysis Platform to Assess the Identity of Recombinant Adeno-Associated Viral Preparations from Viral DNA Extracts | Human Gene Therapy

Next-generation sequencing (NGS)-guided in vivo selection of a random X...  | Download Scientific Diagram
Next-generation sequencing (NGS)-guided in vivo selection of a random X... | Download Scientific Diagram

Comprehensive Small RNA-Seq of Adeno-Associated Virus (AAV)-Infected Human  Cells Detects Patterns of Novel, Non-Coding AAV RNAs in the Absence of  Cellular miRNA Regulation | PLOS ONE
Comprehensive Small RNA-Seq of Adeno-Associated Virus (AAV)-Infected Human Cells Detects Patterns of Novel, Non-Coding AAV RNAs in the Absence of Cellular miRNA Regulation | PLOS ONE

Analysis of residual DNA by high-throughput sequencing (SSV-Seq) in rAAV  lots - Translational Research in Gene Therapy
Analysis of residual DNA by high-throughput sequencing (SSV-Seq) in rAAV lots - Translational Research in Gene Therapy

Targeted long-read sequencing captures CRISPR editing and AAV integration  outcomes in brain: Molecular Therapy
Targeted long-read sequencing captures CRISPR editing and AAV integration outcomes in brain: Molecular Therapy

The SSV‐Seq 2.0 PCR‐Free Method Improves the Sequencing of Adeno‐Associated  Viral Vector Genomes Containing GC‐Rich Regions and Homopolymers - Lecomte  - 2021 - Biotechnology Journal - Wiley Online Library
The SSV‐Seq 2.0 PCR‐Free Method Improves the Sequencing of Adeno‐Associated Viral Vector Genomes Containing GC‐Rich Regions and Homopolymers - Lecomte - 2021 - Biotechnology Journal - Wiley Online Library

Introduction of AAV : SignaGen Laboratories, A Gene Delivery Company  Providing Custom AAV Adenovirus Lentivirus Production Services &  Manufacturing DNA/siRNA Transfection Reagents..., SignaGen Laboratories, A  Gene Delivery Company Providing Custom AAV ...
Introduction of AAV : SignaGen Laboratories, A Gene Delivery Company Providing Custom AAV Adenovirus Lentivirus Production Services & Manufacturing DNA/siRNA Transfection Reagents..., SignaGen Laboratories, A Gene Delivery Company Providing Custom AAV ...

Optimizing AAV Plasmid Preparation & ITR Sequencing | Azenta Life Sciences
Optimizing AAV Plasmid Preparation & ITR Sequencing | Azenta Life Sciences

HiFi sequencing tools to help transform AAV-based gene therapy - PacBio
HiFi sequencing tools to help transform AAV-based gene therapy - PacBio

Frontiers | The Role of Recombinant AAV in Precise Genome Editing
Frontiers | The Role of Recombinant AAV in Precise Genome Editing

Single-cell RNA sequencing of AAV reveals new insights | CLOVER Center
Single-cell RNA sequencing of AAV reveals new insights | CLOVER Center

Advanced Characterization of DNA Molecules in rAAV Vector Preparations by  Single-stranded Virus Next-generation Sequencing: Molecular Therapy -  Nucleic Acids
Advanced Characterization of DNA Molecules in rAAV Vector Preparations by Single-stranded Virus Next-generation Sequencing: Molecular Therapy - Nucleic Acids

AAV Vector Quality Control: Going the Extra Mile with NGS
AAV Vector Quality Control: Going the Extra Mile with NGS

Pathogens | Free Full-Text | Fantastic AAV Gene Therapy Vectors and How to  Find Them—Random Diversification, Rational Design and Machine Learning
Pathogens | Free Full-Text | Fantastic AAV Gene Therapy Vectors and How to Find Them—Random Diversification, Rational Design and Machine Learning

Structural characterization of a novel human adeno-associated virus capsid  with neurotropic properties | Nature Communications
Structural characterization of a novel human adeno-associated virus capsid with neurotropic properties | Nature Communications

GENEWIZ from Azenta | AAV Plasmid Preparation
GENEWIZ from Azenta | AAV Plasmid Preparation

Library preparation for third-generation PacBio sequencing of AAV... |  Download Scientific Diagram
Library preparation for third-generation PacBio sequencing of AAV... | Download Scientific Diagram

Research Interests | OHSU
Research Interests | OHSU