![Introduction of AAV : SignaGen Laboratories, A Gene Delivery Company Providing Custom AAV Adenovirus Lentivirus Production Services & Manufacturing DNA/siRNA Transfection Reagents..., SignaGen Laboratories, A Gene Delivery Company Providing Custom AAV ... Introduction of AAV : SignaGen Laboratories, A Gene Delivery Company Providing Custom AAV Adenovirus Lentivirus Production Services & Manufacturing DNA/siRNA Transfection Reagents..., SignaGen Laboratories, A Gene Delivery Company Providing Custom AAV ...](http://signagen.com/images/AAV2_ITR.jpg)
Introduction of AAV : SignaGen Laboratories, A Gene Delivery Company Providing Custom AAV Adenovirus Lentivirus Production Services & Manufacturing DNA/siRNA Transfection Reagents..., SignaGen Laboratories, A Gene Delivery Company Providing Custom AAV ...
![Introduction of AAV : SignaGen Laboratories, A Gene Delivery Company Providing Custom AAV Adenovirus Lentivirus Production Services & Manufacturing DNA/siRNA Transfection Reagents..., SignaGen Laboratories, A Gene Delivery Company Providing Custom AAV ... Introduction of AAV : SignaGen Laboratories, A Gene Delivery Company Providing Custom AAV Adenovirus Lentivirus Production Services & Manufacturing DNA/siRNA Transfection Reagents..., SignaGen Laboratories, A Gene Delivery Company Providing Custom AAV ...](http://signagen.com/images/rAAV_Packaging.jpg)
Introduction of AAV : SignaGen Laboratories, A Gene Delivery Company Providing Custom AAV Adenovirus Lentivirus Production Services & Manufacturing DNA/siRNA Transfection Reagents..., SignaGen Laboratories, A Gene Delivery Company Providing Custom AAV ...
![Sequence alignment of the RBS and TRS of the AAV2 ITR and the AAV2 p5... | Download Scientific Diagram Sequence alignment of the RBS and TRS of the AAV2 ITR and the AAV2 p5... | Download Scientific Diagram](https://www.researchgate.net/publication/7603069/figure/fig1/AS:281337043931144@1444087386349/Sequence-alignment-of-the-RBS-and-TRS-of-the-AAV2-ITR-and-the-AAV2-p5-promoter-The-25-bp.png)
Sequence alignment of the RBS and TRS of the AAV2 ITR and the AAV2 p5... | Download Scientific Diagram
![Adeno-associated Virus Genome Population Sequencing Achieves Full Vector Genome Resolution and Reveals Human-Vector Chimeras: Molecular Therapy - Methods & Clinical Development Adeno-associated Virus Genome Population Sequencing Achieves Full Vector Genome Resolution and Reveals Human-Vector Chimeras: Molecular Therapy - Methods & Clinical Development](https://www.cell.com/cms/attachment/09356f9a-aec4-4ff8-bcae-4fd8cc4f311b/gr1.jpg)
Adeno-associated Virus Genome Population Sequencing Achieves Full Vector Genome Resolution and Reveals Human-Vector Chimeras: Molecular Therapy - Methods & Clinical Development
![AAV Vector Transduction Restriction and Attenuated Toxicity in hESCs via a Rationally Designed Inverted Terminal Repeat | bioRxiv AAV Vector Transduction Restriction and Attenuated Toxicity in hESCs via a Rationally Designed Inverted Terminal Repeat | bioRxiv](https://www.biorxiv.org/content/biorxiv/early/2022/06/30/2022.06.30.498264/F1.large.jpg)
AAV Vector Transduction Restriction and Attenuated Toxicity in hESCs via a Rationally Designed Inverted Terminal Repeat | bioRxiv
![Deletion of the B-B' and C-C' regions of inverted terminal repeats reduces rAAV productivity but increases transgene expression | Scientific Reports Deletion of the B-B' and C-C' regions of inverted terminal repeats reduces rAAV productivity but increases transgene expression | Scientific Reports](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41598-017-04054-4/MediaObjects/41598_2017_4054_Fig1_HTML.jpg)
Deletion of the B-B' and C-C' regions of inverted terminal repeats reduces rAAV productivity but increases transgene expression | Scientific Reports
![Structure of the wild-type AAV2 and modified ITR. (A) The AAV2 ITR is... | Download Scientific Diagram Structure of the wild-type AAV2 and modified ITR. (A) The AAV2 ITR is... | Download Scientific Diagram](https://www.researchgate.net/publication/46180159/figure/fig1/AS:203022572494851@1425415761904/Structure-of-the-wild-type-AAV2-and-modified-ITR-A-The-AAV2-ITR-is-composed-of-seven.png)
Structure of the wild-type AAV2 and modified ITR. (A) The AAV2 ITR is... | Download Scientific Diagram
![Inverted terminal repeat (ITR) structure. (A) Secondary structure of... | Download Scientific Diagram Inverted terminal repeat (ITR) structure. (A) Secondary structure of... | Download Scientific Diagram](https://www.researchgate.net/publication/225051920/figure/fig5/AS:668345166733328@1536357313791/Inverted-terminal-repeat-ITR-structure-A-Secondary-structure-of-the-AAV-2-3-ITR.png)
Inverted terminal repeat (ITR) structure. (A) Secondary structure of... | Download Scientific Diagram
![Adeno-associated virus (AAV) site-specific recombination does not require a Rep-dependent origin of replication within the AAV terminal repeat | PNAS Adeno-associated virus (AAV) site-specific recombination does not require a Rep-dependent origin of replication within the AAV terminal repeat | PNAS](https://www.pnas.org/cms/10.1073/pnas.241508998/asset/563055dc-eae0-4a8d-b7d7-3c94c5e38c2c/assets/graphic/pq2415089001.jpeg)
Adeno-associated virus (AAV) site-specific recombination does not require a Rep-dependent origin of replication within the AAV terminal repeat | PNAS
![Helper-independent and AAV-ITR-independent chromosomal integration of double-stranded linear DNA vectors in mice: Molecular Therapy Helper-independent and AAV-ITR-independent chromosomal integration of double-stranded linear DNA vectors in mice: Molecular Therapy](https://www.cell.com/cms/attachment/2075875101/2069915647/gr1.jpg)
Helper-independent and AAV-ITR-independent chromosomal integration of double-stranded linear DNA vectors in mice: Molecular Therapy
![ITR-Seq, a next-generation sequencing assay, identifies genome-wide DNA editing sites in vivo following adeno-associated viral vector-mediated genome editing | BMC Genomics | Full Text ITR-Seq, a next-generation sequencing assay, identifies genome-wide DNA editing sites in vivo following adeno-associated viral vector-mediated genome editing | BMC Genomics | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs12864-020-6655-4/MediaObjects/12864_2020_6655_Fig1_HTML.png)
ITR-Seq, a next-generation sequencing assay, identifies genome-wide DNA editing sites in vivo following adeno-associated viral vector-mediated genome editing | BMC Genomics | Full Text
![Schematic representation of an AAV vector and inverted terminal repeats... | Download Scientific Diagram Schematic representation of an AAV vector and inverted terminal repeats... | Download Scientific Diagram](https://www.researchgate.net/publication/230894469/figure/fig1/AS:300634940166148@1448688363462/Schematic-representation-of-an-AAV-vector-and-inverted-terminal-repeats-ITR-A.png)
Schematic representation of an AAV vector and inverted terminal repeats... | Download Scientific Diagram
![Universal Real-Time PCR for the Detection and Quantification of Adeno-Associated Virus Serotype 2-Derived Inverted Terminal Repeat Sequences | Human Gene Therapy Methods Universal Real-Time PCR for the Detection and Quantification of Adeno-Associated Virus Serotype 2-Derived Inverted Terminal Repeat Sequences | Human Gene Therapy Methods](https://www.liebertpub.com/cms/10.1089/hgtb.2011.034/asset/images/medium/figure1.gif)
Universal Real-Time PCR for the Detection and Quantification of Adeno-Associated Virus Serotype 2-Derived Inverted Terminal Repeat Sequences | Human Gene Therapy Methods
![AAV5 ITR. The sequence of the ITR is shown in the hairpin conformation.... | Download Scientific Diagram AAV5 ITR. The sequence of the ITR is shown in the hairpin conformation.... | Download Scientific Diagram](https://www.researchgate.net/publication/13407323/figure/fig4/AS:601635797622821@1520452560915/AAV5-ITR-The-sequence-of-the-ITR-is-shown-in-the-hairpin-conformation-The-putative-Rep.png)
AAV5 ITR. The sequence of the ITR is shown in the hairpin conformation.... | Download Scientific Diagram
![The Nuclease Domain of Adeno-Associated Virus Rep Coordinates Replication Initiation Using Two Distinct DNA Recognition Interfaces: Molecular Cell The Nuclease Domain of Adeno-Associated Virus Rep Coordinates Replication Initiation Using Two Distinct DNA Recognition Interfaces: Molecular Cell](https://www.cell.com/cms/asset/7e1e4a95-795c-4f7b-ac76-add00ef89bd3/gr1.jpg)