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Is Adjuvant Pembrolizumab Clinically Valuable?
Is Adjuvant Pembrolizumab Clinically Valuable?

Pembrolizumab versus placebo as adjuvant therapy for completely resected  stage IB–IIIA non-small-cell lung cancer (PEARLS/KEYNOTE-091): an interim  analysis of a randomised, triple-blind, phase 3 trial - The Lancet Oncology
Pembrolizumab versus placebo as adjuvant therapy for completely resected stage IB–IIIA non-small-cell lung cancer (PEARLS/KEYNOTE-091): an interim analysis of a randomised, triple-blind, phase 3 trial - The Lancet Oncology

Schema of the ACCIO trial including three arms. Pembrolizumab dosing is...  | Download Scientific Diagram
Schema of the ACCIO trial including three arms. Pembrolizumab dosing is... | Download Scientific Diagram

Oncology Brothers on Twitter: "1. #KN091 #PEARLS by @peters_solange :  Pembrolizumab in adjuvant settings and after chemotherapy for stage IB (T2a  ≥4 cm), II, or IIIA NSCLC. Approved for PDL1 expressions. -
Oncology Brothers on Twitter: "1. #KN091 #PEARLS by @peters_solange : Pembrolizumab in adjuvant settings and after chemotherapy for stage IB (T2a ≥4 cm), II, or IIIA NSCLC. Approved for PDL1 expressions. -

Frühes nichtkleinzelliges Bronchialkarzinom: Pembrolizumab adjuvant nach  Resektion verlängert das krankheitsfreie Überleben
Frühes nichtkleinzelliges Bronchialkarzinom: Pembrolizumab adjuvant nach Resektion verlängert das krankheitsfreie Überleben

Pembrolizumab in Metastatic Non–Small-Cell Lung Cancer | NEJM Resident 360
Pembrolizumab in Metastatic Non–Small-Cell Lung Cancer | NEJM Resident 360

Stephen V Liu, MD on Twitter: "#ASCO22 Discussion of PEARLS (KEYNOTE-091,  @ETOP_eu 8-15), a phase III study of adjuvant pembrolizumab in resected  NSCLC. The study did meet its primary endpoint (DFS HR
Stephen V Liu, MD on Twitter: "#ASCO22 Discussion of PEARLS (KEYNOTE-091, @ETOP_eu 8-15), a phase III study of adjuvant pembrolizumab in resected NSCLC. The study did meet its primary endpoint (DFS HR

ES/ONCO/1118/0300. - ppt download
ES/ONCO/1118/0300. - ppt download

Frontiers | Adjuvant immunotherapy in early-stage resectable non–small cell  lung cancer: A new milestone
Frontiers | Adjuvant immunotherapy in early-stage resectable non–small cell lung cancer: A new milestone

The cutting-edge progress of immune-checkpoint blockade in lung cancer |  Cellular & Molecular Immunology
The cutting-edge progress of immune-checkpoint blockade in lung cancer | Cellular & Molecular Immunology

Aakash Desai, MD, MPH on Twitter: "@LuisPaz_Ares discussed data from #PEARLS  study #Pembrolizumab for early stage #NSCLC #LCSM with dual primary  endpoint of DFS in all comers/PDL1>50%, showing significant DFS  improvement HR:0.76
Aakash Desai, MD, MPH on Twitter: "@LuisPaz_Ares discussed data from #PEARLS study #Pembrolizumab for early stage #NSCLC #LCSM with dual primary endpoint of DFS in all comers/PDL1>50%, showing significant DFS improvement HR:0.76

KURZPROTOKOLL PEARLS
KURZPROTOKOLL PEARLS

Pembrolizumab in Early-Stage Non-Small Cell Lung Cancer After Complete  Resection
Pembrolizumab in Early-Stage Non-Small Cell Lung Cancer After Complete Resection

Treatment benefits and outcome determinants in (neo)adjuvant trials -  memoinOncology
Treatment benefits and outcome determinants in (neo)adjuvant trials - memoinOncology

FDA OKs Adjuvant Pembrolizumab for NSCLC | MedPage Today
FDA OKs Adjuvant Pembrolizumab for NSCLC | MedPage Today

Pembrolizumab versus placebo as adjuvant therapy for completely resected  stage IB–IIIA non-small-cell lung cancer (PEARLS/KEYNOTE-091): an interim  analysis of a randomised, triple-blind, phase 3 trial | AIOM
Pembrolizumab versus placebo as adjuvant therapy for completely resected stage IB–IIIA non-small-cell lung cancer (PEARLS/KEYNOTE-091): an interim analysis of a randomised, triple-blind, phase 3 trial | AIOM

Pembrolizumab versus placebo as adjuvant therapy for completely resected  stage IB–IIIA non-small-cell lung cancer (PEARLS/KEYNOTE-091): an interim  analysis of a randomised, triple-blind, phase 3 trial | AIOM
Pembrolizumab versus placebo as adjuvant therapy for completely resected stage IB–IIIA non-small-cell lung cancer (PEARLS/KEYNOTE-091): an interim analysis of a randomised, triple-blind, phase 3 trial | AIOM

PEARLS/KENOTE-091】 完全切除後のぺムブロリズマブは有意に無病生存期間を延長 - キュート先生の『肺癌勉強会』
PEARLS/KENOTE-091】 完全切除後のぺムブロリズマブは有意に無病生存期間を延長 - キュート先生の『肺癌勉強会』

Immune Checkpoint Inhibitors in Thoracic Malignancies: Review of the  Existing Evidence by an IASLC Expert Panel and Recommendations -  ScienceDirect
Immune Checkpoint Inhibitors in Thoracic Malignancies: Review of the Existing Evidence by an IASLC Expert Panel and Recommendations - ScienceDirect

Adjuvant Pembrolizumab Approval Adds to Prevention of Recurrent NSCLC
Adjuvant Pembrolizumab Approval Adds to Prevention of Recurrent NSCLC

HCP Toolkits - AIM with Immunotherapy - Immuno-Oncology Essentials
HCP Toolkits - AIM with Immunotherapy - Immuno-Oncology Essentials

Adjuvant Immunotherapy Approved for Lung Cancer - NCI
Adjuvant Immunotherapy Approved for Lung Cancer - NCI

Pembrolizumab versus placebo as adjuvant therapy for completely resected  stage IB–IIIA non-small-cell lung cancer (PEARLS/KEYNOTE-091): an interim  analysis of a randomised, triple-blind, phase 3 trial - The Lancet Oncology
Pembrolizumab versus placebo as adjuvant therapy for completely resected stage IB–IIIA non-small-cell lung cancer (PEARLS/KEYNOTE-091): an interim analysis of a randomised, triple-blind, phase 3 trial - The Lancet Oncology

癌免疫療法による周術期治療で呼吸器外科の治療体系は変わる(2ページ目):日経メディカル
癌免疫療法による周術期治療で呼吸器外科の治療体系は変わる(2ページ目):日経メディカル

PEARLS/KEYNOTE-091: Pembrolizumab vs placebo in early-stage NSCLC
PEARLS/KEYNOTE-091: Pembrolizumab vs placebo in early-stage NSCLC